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MEDICAL ANIMATION TRANSCRIPT: A typical neuron consists of a cell body, plasma membrane extensions called dendrites, an elongated fiber known as an axon, and an axon hillock, the trigger zone that releases a nerve impulse. The axon hillock maintains an excitation limit, or threshold, which determines whether or not a neuron will generate a nerve impulse. A nerve impulse is an electrical signal conducted by a neuron, causing a response in another neuron or target cell. When a neuron is at rest, its membrane is polarized because there are more positive ions outside the cell and more negative ions inside the cell, which creates a charge difference across the membrane. Active transport mechanisms called sodium-potassium pumps carry more sodium and less potassium ions across the membrane to maintain this charged difference. Even in a resting neuron, there is the potential for the charged difference to create an electrical current. This is called a resting membrane potential. When an electrical current flows through a dendrite, this is called a local membrane potential. When a dendrite detects a stimulus, a sodium channel in its plasma membrane opens and lets sodium into the neuron. This influx of positive ions reverses the charge across a particular section of the membrane in a process called depolarization. To repolarize the membrane, potassium channels open and release potassium out of the neuron. Nearby, a sodium-potassium pump transports excess sodium amount and brings potassium in, which restores the resting membrane potential. The flow of reversing charges along the dendrite's membrane produces a wavelike electrical current toward the neuron's trigger zone. If the strength of the current meets or exceeds the threshold at the trigger zone, an electrical signal called an action potential or nerve impulse will occur. In a nerve impulse, the trigger zone sends an electrical signal down the axon toward the space between neurons called a synapse or to a target cell membrane. ♪ [music] ♪
"Thank you for the wonderful illustrations. The case resulted in a defense verdict last Friday. I know [our medical expert witness] presented some challenges for you and I appreciate how you were able to work with him."
Robert F. Donnelly
Goodman Allen & Filetti, PLLC
Richmond, VA
"Medical illustrations are essential during trial for any medical malpractice case. The people at MLA have the uncanny ability of creating medical illustrations that simplify the most complex of medical concepts and human anatomy to a lay audience. The exhibits of MLA allow experts to easily describe complex concepts and human anatomy in a manner that could
not be done otherwise.
In addition, their custom illustrations show in great detail the extent of
injuries suffered and the devastating effects they have had on the client's
anatomy. These custom illustration can show, side by side, the body before
and after a catastrophic injury. The effect of this juxtaposition is
unmatched by any testimony that can be adduced at the time of trial.
Even jurors after trial have commented on the ease with which they grasp
medical concepts and anatomy once the MLA exhibits were introduced and
used by my experts. Even judges who have "seen it all" are thoroughly
impressed by the detail and sophistication of the illustrations.
"You and your company are wonderful. Your service, turnaround time, quality
and price were better than I could have asked for. Please add me to your
long list of satisfied customers."
Robert F. Linton, Jr.
Linton & Hirshman
Cleveland, OH
"For modern audiences, it is absolutely essential to use medical
demonstrative evidence to convey the severity and extent of physical
injuries to a jury. Your company's high quality illustrations of our
client's discectomy surgery, combined with strong expert testimony, allowed
the jury to fully appreciate the significance of our client's injuries.
We are very pleased with a verdict exceeding $297,000.00, far in excess of
the $20,000.00 initially offered by the defendant. The medical demonstrative
evidence provided by Medical Legal Art was an asset we could not have
afforded to have been without."
Medical Legal Art creates medical demonstrative evidence (medical
illustrations, drawings, pictures, graphics, charts, medical animations,
anatomical models, and interactive presentations) for use during legal
proceedings, including research, demand letters, client conferences,
depositions, arbitrations, mediations, settlement conferences, mock jury
trials and for use in the courtroom. We do not provide legal or medical
advice. If you have legal questions, you should find a lawyer with whom you
can discuss your case issues. If you have medical questions, you should seek the advice of a healthcare provider.